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ISSN : 1225-0171(Print)
ISSN : 2287-545X(Online)
ISSN : 2287-545X(Online)
Korean Journal of Applied Entomology Vol.65 No.1 pp.81-90
DOI : https://doi.org/10.5656/KSAE.2025.12.0.039
DOI : https://doi.org/10.5656/KSAE.2025.12.0.039
Assessment of Resistance Development to Botanical Phenylpropanoid in a Laboratory Strain of Drosophila melanogaster
Abstract
Essential oils derived from natural products are gaining attention as alternatives to synthetic insecticides, and their components exhibit fumigant activity as well as diverse physiological effects that contribute to pest control. In this study, we evaluated resistance development, detoxification enzyme activity, and fitness costs in adult Drosophila melanogaster following repeated exposure to two representative phenylpropanoids, trans-cinnamaldehyde and trans-anethole. Selection pressure was applied using a topical application method. The trans-anethole-selected strain maintained a resistance ratio (RR) around 1 throughout ten generations, whereas the trans-cinnamaldehyde-selected strain showed an increase in RR up to 2.51. Although these values are much lower than those observed for conventional synthetic insecticides, they suggest that resistance can still develop even to single natural compounds. Detoxification enzyme assays revealed compound-specific changes in esterase and glutathione S-transferase (GST) activities, which may be attributed to differences in chemical structure as well as concentration-dependent physiological responses. Overall, this study demonstrates that repeated exposure to natural product components can induce resistance development in insects and suggests that mixture-based applications may be more effective than single compounds for delaying resistance evolution.
초록
Vol. 40 No. 4 (2022.12)
Frequency Quarterly
Doi Prefix 10.5656/KSAE
Year of Launching 1962
Publisher Korean Society of Applied Entomology
Online Submission
submission.entomology2.or.kr
KSAE
The Korean Society of Applied Entomology
